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Is it healthy or harmful to be in ketosis? This guide provides all the information you need about ketosis, including its benefits, potential risks, and tips for successfully getting into ketosis and staying there. What is ketosis? Ketosis is a metabolic state in which your body uses fat and ketones rather than glucose sugar as its main fuel source. Glucose is stored in your liver and released as needed for energy. However, after carb intake has been extremely low for one to two days, these glucose stores become depleted. In ketosis, your body produces ketones at an accelerated rate. Ketones, or ketone bodies, are made by your liver from fat that you eat and your own body fat. The three ketone bodies are beta-hydroxybutyrate BHB, acetoacetate, and acetone although acetone is technically a breakdown product of acetoacetate.