Non-diabetic ketoacidosis is a rare condition which can be caused by starvation. Lack of glucose can force the body into ketogenesis causing a metabolic acidosis. As previously reported in the literature, ketoacidosis might, on rare occasions, be caused by a diet with low carbohydrate content. However, to the best of our knowledge this is the first reported case in the literature of ketoacidosis, in a non-diabetic patient, associated with a combination of low carbohydrate, high fat diet and lactation. A healthy non-diabetic, year old white woman started a low carbohydrate, high fat diet when she was breastfeeding her son of 10 months of age. After 10 days she was admitted to our hospital with nausea and vomiting and a serum pH of 7. Clinical signs and blood samples were compatible with ketoacidosis. She was given fluids intravenously and insulin. No anamnestic or clinical signs of diabetes were found. She recovered quickly and was discharged 3 days later.
By Kara Miecznikowski. While ketosis and ketoacidosis sound quite similar — and both describe elevated ketones in the blood — there are critical differences. Ketosis may be a normal, safe body response to low-carbohydrate diets or not eating for a certain period of time fasting. On the other hand, ketoacidosis can be a dangerous and life-threatening complication where too many ketones will make your blood acidic. Ketones are produced from fat and can be used as an alternative source of energy for the body when its cells are low on glucose sugar for a period of time. In response, the body releases fat stored in fat cells. The fat then travels to the liver, where it is broken down into ketones, which are used as one source of alternative energy instead of glucose. Ketosis is when ketones accumulate in your blood. This is usually not problematic. Ketosis can occur when a person is fasting or following a very low-carbohydrate diet, sometimes called a ketogenic diet. Low-carbohydrate diets may be used to purposely achieve ketosis — reducing carbohydrates to fewer than 50 grams per day has been shown to result in weight loss and A1C reduction. If you have type 1 diabetes, there is no way to know if ketosis is caused just by fasting or by an insufficient amount of insulin.
In previous diet of acidosis, in lactating non-diabetic women as well as in other non-diabetic patients, physiological stressors such as fasting, infections, lactating twins and recently even bariatric keto have been considered to be the push factor into ketoacidosis [ caused — 14 ]. Find articles by Alina Kifayat. Endocr J. Wilbert S. This is likely what happened to our patient. External link. Isnt warn against kfto drinking during the pandemic.